Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa

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Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa

PURPOSE To describe the peripheral autofluorescence images and clinical features of patients with retinal dystrophy who showed radial fundus autofluorescence (FAF) at the posterior pole. METHODS The authors retrospectively reviewed pooled wide-field FAF images of 711 patients with retinal dystrophy and 56 family members. RESULTS Eleven eyes of seven women exhibited radial FAF at the posteri...

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Quantifying Fundus Autofluorescence in Patients With Retinitis Pigmentosa

Purpose Using quantitative fundus autofluorescence (qAF), we analyzed short-wavelength autofluorescent (SW-AF) rings in RP. Methods Short-wavelength autofluorescent images (486 nm excitation) of 40 patients with RP (69 eyes) were acquired with a confocal scanning laser ophthalmoscope equipped with an internal fluorescent reference. Mean qAF was measured in eight preset segments (qAF8) and in ...

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Fundus Autofluorescence Lifetime Patterns in Retinitis Pigmentosa.

Purpose We investigated whether fundus autofluorescence (FAF) lifetimes in patients with retinitis pigmentosa display a disease-specific lifetime pattern. Methods Fundus autofluorescence lifetime imaging ophthalmoscopy (FLIO) was performed in two spectral channels (498-560 and 560-720 nm) after excitation with a 473 nm pulsed laser in patients with retinitis pigmentosa and compared to healthy...

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X-linked retinitis pigmentosa.

Of 107 consecutive patients with genetically-determined retinitis pigmentosa, 23 were provisionally diagnosed as having inherited the disease in an X-linked fashion. 42 affected males and 61 females were examined, and from the data obtained the following conclusions were drawn: (1) X-linked retinitis pigmentosa exists and is distinct from choroideremia. (2) In contrast to the results of previou...

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Comparison of fundus autofluorescence with photopic and scotopic fine-matrix mapping in patients with retinitis pigmentosa and normal visual acuity.

PURPOSE To compare psychophysically determined spatial variations in photopic and scotopic sensitivity across the macula in patients with retinitis pigmentosa (RP) and normal visual acuity who manifest an abnormal high-density ring of fundus autofluorescence (AF). METHODS Eleven patients with a clinical diagnosis of RP were examined. All had rod-cone dystrophy (International Society for Clini...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2015

ISSN: 1177-5483

DOI: 10.2147/opth.s89371